Individual asbestos exposure: smoking and mortality--a cohort study in the asbestos cement industry.
نویسندگان
چکیده
A historical prospective cohort study comprised all persons employed from 1950 to 1981 for at least three years in the oldest asbestos cement factory in the world. From 2816 persons eligible for the study, record based estimates and measurements of dust and fibres and histories of smoking based on interviews were used to calculate individual exposures over time. After observation of 51,218 person-years and registration of 540 deaths, underlying causes of death for this cohort were compared with those for the regional population on the basis of death certificates. Deaths from lung cancer in asbestos cement workers were higher (standard mortality ratio (SMR) 1.7), but after adjustment for age and sex specific smoking habits this was not significant (SMR 1.04). The study had a probability of greater than 92% of detecting a smoking adjusted SMR of 1.5 or more. Using the best available evidence (including necropsy records) 52 deaths were assigned to lung cancer and five to mesothelioma. Life table analyses confirmed the predominant influence of smoking on lung cancer. Mesothelioma was associated with the use of crocidolite in pipe production. From present working conditions with much lower concentrations of chrysotile and no crocidolite no more occupational cancers are expected in the asbestos cement industry.
منابع مشابه
مولفه های شغلی و محیطی در موارد مزوتلیومای بدخیم پلور و تعیین نسبت شانس بروز مزوتلیوما در مواجهه با آزبست
Background and aimsThe relationship between pleural malignant mesothelioma and exposure to asbestos is well-known, but there is no accurate information regarding high risk occupations and types of exposure in Iran. In this study we specified high risk jobs for asbestos exposure.MethodsIn this case-control study, 64 cases with diagnosis of pleural malignant mesothelioma who were admitted in Masi...
متن کاملA cohort study on mortality among wives of workers in the asbestos cement industry in Casale Monferrato, Italy.
The study investigates mortality from cancer and other diseases in a cohort of wives of asbestos cement workers in Casale Monferrato (northwest Italy). After the exclusion of women with an occupational record in the asbestos cement industry, the cohort comprised 1964 women. Their domestic exposure was estimated according to their husbands' periods of employment in the plant: 1740 had a period o...
متن کاملPulmonary function in asbestos cement workers: a dose-response study.
This study has found that residence time weighted exposure (asbestos dose) may be used to model the risk and extent of pulmonary function abnormalities in a cohort of asbestos cement workers. This parameter, which incorporates both exposure concentration and latency, had previously proved useful for modelling the risk of radiographic abnormalities in this cohort. Asbestos dose and smoking were ...
متن کاملمطالعه غلظت و نوع الیاف آزبست با روش میکروسکوپی فاز کنتراست و الکترونی روبشی به منظور تعیین مواجهه شغلی در یک صنعت سیمان- آزبست
Background and aims : Asbestos minerals are divided into two main groups including serpentine and amphiboles and each has one or more subgroups. These minerals have been used in industrial products such as cement-asbestos sheet and pipe, brake shoe, clutch and insulation materials. Occupational and non - occupational exposures by this carcinogenic material have caused to develop several metho...
متن کاملFactsheet on Asbestos and Asbestos-Related Diseases Full text
Objectives: Workers in the asbestos industry tend to have high smoking rates compared to the general population. Both asbestos exposure and cigarette smoking are recognized risk factors for lung cancer mortality, but the exact nature of the interaction between the two remains uncertain. The aim of this study was to examine the effect of smoking and smoking cessation among asbestos workers in Gr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- British journal of industrial medicine
دوره 47 9 شماره
صفحات -
تاریخ انتشار 1990